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Next Generation Sequence Analyst Job - #1575178A3

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Location: Durham, North Carolina, South United States, USA
Company: Syngenta
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Open Til: 11-Apr-12
Industry Sector: Agribusiness
Industry Type: Agronomy
Career Type: General
Job Type: Full Time
Minimum Years Experience Required: N/A
Salary: Competitive

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Division: SBI
Function: Research & Product Development
City: Durham
State/Province: North Carolina [NC]
Country: United States [US]
Position Title: Next Generation Sequence Analyst
Job ID: 2751

Role Purpose/Accountabilities:

- Partner with bench scientists and plant breeders to design and execute state-of-the-art experiments that combine their knowledge of plant biology with the capabilities of next generation sequencing to support lead generation, mode of action research, biomarker discovery and germplasm development
- Provide expert analysis of next generation sequencing data in a variety of areas, such as: genome assembly, transcriptome analysis, genomic structural variation, methylation analysis, small RNA detection, genetic variation, etc.
- Propose and execute new projects and infrastructure improvements that take advantage of the power of next generation sequencing to answer scientific questions
- Determine the optimal analytical tools and databases required to achieve scientific objectives
- Explain complex scientific concepts and results to audiences not closely connected with the field

- Identify and implement cutting edge analytical methods and algorithms from a variety of sources to deliver high quality analysis results for Syngenta scientists across the globe
- Modify existing methods or develop new ones, when necessary, to address scientific questions and support project objectives
- Provide quick, tactical solutions to scientists by writing simple computer programs or scripts
- Support multiple projects simultaneously and deliver results in a timely manner
- Develop best practices for next generation sequencing analysis, document them, and teach others how to execute them
- Contribute to next generation sequencing data analysis infrastructure development and operation

Knowledge, Skills & Experience:

Critical knowledge:
- PhD or equivalent experience in Computational Biology, Bioinformatics, Statistics or related biological field
- Knowledge of the challenges and breadth of analysis in the emerging field of next generation sequencing
- Knowledge of commercial and publicly available bioinformatics tools and data sets
- Familiarity with the Linux and/or Unix computing environments required and previous experience implementing processes in a grid environment such as Sun Grid Engine strongly desired
- Proficiency in Perl or other programming or scripting language required
- Fluency in a statistical programming language such as R or SAS is desired
- Knowledge of SQL query language is desired

Critical experience:
- Three to five years experience (could be postdoctoral) performing computational analysis in a life sciences setting
- Experience working effectively in multi-disciplinary teams
- Working knowledge of information systems and the ability to communicate effectively with IS professionals
- Previous work experience in a biological laboratory, particularly if related to plant biology, would be a plus
- Experience instructing scientists on the use of computational biology tools would be a plus

Critical technical, professional and personal capabilities:
- Ability to translate scientific problems into computational solutions
- Ability to integrate successfully in a team / matrix environment comprising multiple disciplines, nationalities, and cultural backgrounds
- Support fellow team members in the creative process by contributing ideas and providing constructive feedback
- Determination and persistence to work through challenging and complex problems
- Excellent oral and written communication skills for both scientific and non-scientific audiences
- Demonstrated organizational and time management skills

Critical leadership capabilities:
- An ability to gain the respect and cooperation of others and to exert influence without holding an official leadership role
- Ability to bring a project to a successful conclusion
- Willingness to take reasonable risks that push the cutting edge of technology and deliver excellent scientific results
- Ability to thrive in an environment with uncertainty and change

Critical Success Factors & Key Challenges:
- Willingness to continually grow in knowledge of next generation sequencing analysis and plant biology
- Ability to learn new methods of analysis through self-study and collaboration with colleagues
- Maintain awareness of the latest developments in the field of bioinformatics
- Exchange ideas and knowledge with colleagues on the Bioinformatics team to elevate the caliber of science performed within the group
- Participate in a culture of continuous improvement where issues and problems are openly identified and discussed in order to institute positive change
- Willingness to remain flexible, attempt new approaches and adapt to changes in scientific direction
- Understand the scientific and business objectives of the organization

Additional Information:

- All applicants must be eligible to work in the US.
- Infrequent travel, including international travel, may be required.